INTEMA   05428
INSTITUTO DE INVESTIGACIONES EN CIENCIA Y TECNOLOGIA DE MATERIALES
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
An in vitro set up for the assessment of electrospun nanofibrous vascular grafts
Autor/es:
D. SUAREZ BAGNASCO; L. CYMBERKNOP; F. MONTINI BALLARIN; G. BALAY; C.A. NEGREIRA; G.A. ABRAHAM; R.L. ARMENTANO
Lugar:
Paraná, Entre Ríos
Reunión:
Congreso; VI Congreso Latinoamericano de Ingeniería Biomédica (CLAIB 2014); 2014
Institución organizadora:
CLAIB
Resumen:
Introduction: An experimental setup, using gold standard and high resolution ultrasound techniques, was adapted to characterize electrospun vascular grafts in vitro. Materials and Methods: Grafts were subjected to near physiologic pulsatile pressure conditions, following the criteria stated in the international standard for cardiovascular implantstubular vascular prostheses. Results: Internal pressure and external diameter variations of Poly(L-lactic acid) (PLLA) vascular grafts were obtained, allowing the assessment of mechanical parameters. Dynamic compliance was observed to decrease significantly in most cases, as transmural pressure increases. Conclusion: Mechanical characterization of small diameter electrospun PLLA vascular grafts was adequately achieved.